no code implementations • 25 Mar 2024 • Braja Gopal Patra, Lauren A. Lepow, Praneet Kasi Reddy Jagadeesh Kumar, Veer Vekaria, Mohit Manoj Sharma, Prakash Adekkanattu, Brian Fennessy, Gavin Hynes, Isotta Landi, Jorge A. Sanchez-Ruiz, Euijung Ryu, Joanna M. Biernacka, Girish N. Nadkarni, Ardesheer Talati, Myrna Weissman, Mark Olfson, J. John Mann, Alexander W. Charney, Jyotishman Pathak
For extracting subcategories, the RBS also outperformed the LLM at both MSHS (0. 90 vs. 0. 62) and WCM (0. 82 vs. 0. 81).
no code implementations • 6 Dec 2022 • Zehao Yu, Xi Yang, Chong Dang, Prakash Adekkanattu, Braja Gopal Patra, Yifan Peng, Jyotishman Pathak, Debbie L. Wilson, Ching-Yuan Chang, Wei-Hsuan Lo-Ciganic, Thomas J. George, William R. Hogan, Yi Guo, Jiang Bian, Yonghui Wu
Objective: We aim to develop an open-source natural language processing (NLP) package, SODA (i. e., SOcial DeterminAnts), with pre-trained transformer models to extract social determinants of health (SDoH) for cancer patients, examine the generalizability of SODA to a new disease domain (i. e., opioid use), and evaluate the extraction rate of SDoH using cancer populations.
no code implementations • 7 Nov 2022 • Chengsheng Mao, Jie Xu, Luke Rasmussen, Yikuan Li, Prakash Adekkanattu, Jennifer Pacheco, Borna Bonakdarpour, Robert Vassar, Guoqian Jiang, Fei Wang, Jyotishman Pathak, Yuan Luo
Materials and Methods: We identified 3657 patients diagnosed with MCI together with their progress notes from Northwestern Medicine Enterprise Data Warehouse (NMEDW) between 2000-2020.
no code implementations • 10 Aug 2021 • Zehao Yu, Xi Yang, Chong Dang, Songzi Wu, Prakash Adekkanattu, Jyotishman Pathak, Thomas J. George, William R. Hogan, Yi Guo, Jiang Bian, Yonghui Wu
In this study, we examined two state-of-the-art transformer-based NLP models, including BERT and RoBERTa, to extract SBDoH concepts from clinical narratives, applied the best performing model to extract SBDoH concepts on a lung cancer screening patient cohort, and examined the difference of SBDoH information between NLP extracted results and structured EHRs (SBDoH information captured in standard vocabularies such as the International Classification of Diseases codes).
no code implementations • 10 Apr 2019 • Zhen-Xing Xu, Jingyuan Chou, Xi Sheryl Zhang, Yuan Luo, Tamara Isakova, Prakash Adekkanattu, Jessica S. Ancker, Guoqian Jiang, Richard C. Kiefer, Jennifer A. Pacheco, Luke V. Rasmussen, Jyotishman Pathak, Fei Wang
Sub-phenotype III is with average age 65. 07$ \pm 11. 32 $ years, and was characterized moderate loss of kidney excretory function and thus more likely to develop stage II AKI (SCr $1. 69\pm 0. 32$ mg/dL, eGFR $93. 97\pm 56. 53$ mL/min/1. 73$m^2$).
no code implementations • 2 Apr 2019 • Prakash Adekkanattu, Guoqian Jiang, Yuan Luo, Paul R. Kingsbury, Zhen-Xing Xu, Luke V. Rasmussen, Jennifer A. Pacheco, Richard C. Kiefer, Daniel J. Stone, Pascal S. Brandt, Liang Yao, Yizhen Zhong, Yu Deng, Fei Wang, Jessica S. Ancker, Thomas R. Campion, Jyotishman Pathak
While the NLP system showed high precision and recall measurements for four target concepts (aortic valve regurgitation, left atrium size at end systole, mitral valve regurgitation, tricuspid valve regurgitation) across all sites, we found moderate or poor results for the remaining concepts and the NLP system performance varied between individual sites.