Perineural Invasion Detection in Multiple Organ Cancer Based on Deep Convolutional Neural Network

23 Oct 2021  ·  Ramin Nateghi, Fattaneh Pourakpour ·

Perineural invasion (PNI) by malignant tumor cells has been reported as an independent indicator of poor prognosis in various cancers. Assessment of PNI in small nerves on glass slides is a labor-intensive task. In this study, we propose an algorithm to detect the perineural invasions in colon, prostate, and pancreas cancers based on a convolutional neural network (CNN).

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