no code implementations • 8 Feb 2021 • Patrick Chan, Katherine Johnston, Anne Shiu, Aleksandra Sobieska, Clare Spinner
We first consider the conjecture of Gross et al. that states that removing a leak from an identifiable model yields a model that is again identifiable.
Dynamical Systems Combinatorics 92C45, 37N25, 93B30
no code implementations • 29 Apr 2020 • Nida Obatake, Anne Shiu, Dilruba Sofia
An important invariant of a chemical reaction network is its maximum number of positive steady states.
1 code implementation • 31 Oct 2019 • Carsten Conradi, Nida Obatake, Anne Shiu, Xiaoxian Tang
We consider a model of extracellular signal-regulated kinase (ERK) regulation by dual-site phosphorylation and dephosphorylation, which exhibits bistability and oscillations, but loses these properties in the limit in which the mechanisms underlying phosphorylation and dephosphorylation become processive.