QComp: A QSAR-Based Data Completion Framework for Drug Discovery

no code implementations • 20 May 2024 • Bingjia Yang, Yunsie Chung, Archer Y. Yang, Bo Yuan, Xiang Yu

In drug discovery, in vitro and in vivo experiments reveal biochemical activities related to the efficacy and toxicity of compounds.

MixEHR-SurG: a joint proportional hazard and guided topic model for inferring mortality-associated topics from electronic health records

1 code implementation • 20 Dec 2023 • Yixuan Li, Archer Y. Yang, Ariane Marelli, Yue Li

This leads to a highly interpretable survival topic model that can infer PheCode-specific phenotype topics associated with patient mortality.

Mortality Prediction Survival Analysis

Structured Learning in Time-dependent Cox Models

1 code implementation • 21 Jun 2023 • Guanbo Wang, Yi Lian, Archer Y. Yang, Robert W. Platt, Rui Wang, Sylvie Perreault, Marc Dorais, Mireille E. Schnitzer

We propose a flexible framework for variable selection in time-dependent Cox models, accommodating complex selection rules.

Survival Analysis Variable Selection