no code implementations • 15 May 2024 • Consuelo D. Quinto-Cortés, Carmina Barberena Jonas, Sofía Vieyra-Sánchez, Stephen Oppenheimer, Ram González-Buenfil, Kathryn Auckland, Kathryn Robson, Tom Parks, J. Víctor Moreno-Mayar, Javier Blanco-Portillo, Julian R. Homburger, Genevieve L. Wojcik, Alissa L. Severson, Jonathan S. Friedlaender, Francoise Friedlaender, Angela Allen, Stephen Allen, Mark Stoneking, Adrian V. S. Hill, George Aho, George Koki, William Pomat, Carlos D. Bustamante, Maude Phipps, Alexander J. Mentzer, Andrés Moreno-Estrada, Alexander G. Ioannidis
Encompassing regions that were amongst the first inhabited by humans following the out-of-Africa expansion, hosting populations with the highest levels of archaic hominid introgression, and including Pacific islands that are the most isolated inhabited locations on the planet, Oceania has a rich, but understudied, human genomic landscape.
no code implementations • 6 Dec 2022 • Alexander G. Ioannidis, Javier Blanco-Portillo, Erika Hagelberg, Juan Esteban Rodríguez-Rodríguez, Keolu Fox, Adrian V. S. Hill, Carlos D. Bustamante, Marcus W. Feldman, Alexander J. Mentzer, Andrés Moreno-Estrada
By demonstrating the role that historical population replacements and waves of admixture have played around the world, the genetics work of Reich and colleagues has provided a paradigm for understanding human history [Reich et al. 2009; Reich et al. 2012; Patterson et al. 2012].
1 code implementation • 24 Sep 2019 • Allen Nie, Arturo L. Pineda, Matt W. Wright Hannah Wand, Bryan Wulf, Helio A. Costa, Ronak Y. Patel, Carlos D. Bustamante, James Zou
In collaboration with the Clinical Genomic Resource (ClinGen)---the flagship NIH program for clinical curation---we propose the first machine learning system, LitGen, that can retrieve papers for a particular variant and filter them by specific evidence types used by curators to assess for pathogenicity.
1 code implementation • 28 Jun 2018 • Allen Nie, Ashley Zehnder, Rodney L. Page, Arturo L. Pineda, Manuel A. Rivas, Carlos D. Bustamante, James Zou
However, clinicians lack the time and resource to annotate patient records with standard medical diagnostic codes and most veterinary visits are captured in free text notes.
no code implementations • 9 May 2018 • Bo Wang, Armin Pourshafeie, Marinka Zitnik, Junjie Zhu, Carlos D. Bustamante, Serafim Batzoglou, Jure Leskovec
Networks are ubiquitous in biology where they encode connectivity patterns at all scales of organization, from molecular to the biome.