no code implementations • 30 Apr 2024 • Fanhao Wang, Yuzhe Wang, Laiyi Feng, Changsheng Zhang, Luhua Lai
Despite the exciting progress in target-specific de novo protein binder design, peptide binder design remains challenging due to the flexibility of peptide structures and the scarcity of protein-peptide complex structure data.
no code implementations • 20 Feb 2023 • Chunyu Pan, Zhao Su, Haoyu Zheng, Changsheng Zhang, Weixiong Zhang, Xizhe Zhang
However, the efficacy of the incumbent MDS may diminish as the network topologies evolve.
