Improving Opioid Use Disorder Risk Modelling through Behavioral and Genetic Feature Integration

1 code implementation • 19 Sep 2023 • Sybille Légitime, Kaustubh Prabhu, Devin McConnell, Bing Wang, Dipak K. Dey, Derek Aguiar

Opioids are an effective analgesic for acute and chronic pain, but also carry a considerable risk of addiction leading to millions of opioid use disorder (OUD) cases and tens of thousands of premature deaths in the United States yearly.

Decision Making Experimental Design

Bayesian Reconstruction and Differential Testing of Excised mRNA

1 code implementation • 14 Nov 2022 • Marjan Hosseini, Devin McConnell, Derek Aguiar

We show that BREM achieves higher F1 score for reconstruction tasks and improved accuracy and sensitivity in differential splicing when compared with four state-of-the-art transcript and local splicing methods on simulated data.