Search Results for author: Dongjun Chung

Found 4 papers, 1 papers with code

Statistical Power Analysis for Designing Bulk, Single-Cell, and Spatial Transcriptomics Experiments: Review, Tutorial, and Perspectives

no code implementations7 Jan 2023 Hyeongseon Jeon, Juan Xie, Yeseul Jeon, Kyeong Joo Jung, Arkobrato Gupta, Won Chang, Dongjun Chung

In this paper, we review and discuss the power analysis for three types of gene expression profiling technologies from a practical standpoint, including bulk RNA-seq, single-cell RNA-seq, and high-throughput spatial transcriptomics.

graph-GPA 2.0: A Graphical Model for Multi-disease Analysis of GWAS Results with Integration of Functional Annotation Data

no code implementations14 Apr 2022 Qiaolan Deng, Jin Hyun Nam, Ayse Selen Yilmaz, Won Chang, Maciej Pietrzak, Lang Li, Hang J. Kim, Dongjun Chung

These results demonstrate that GGPA 2. 0 can be a powerful tool to identify associated variants associated with each phenotype or those shared across multiple phenotypes, while also promoting understanding of functional mechanisms underlying the associated variants.

Literature Mining

GPA-Tree: Statistical Approach for Functional-Annotation-Tree-Guided Prioritization of GWAS Results

no code implementations12 Jun 2021 Aastha Khatiwada, Bethany J. Wolf, Ayse Selen Yilmaz, Paula S. Ramos, Maciej Pietrzak, Andrew Lawson, Kelly J. Hunt, Hang J. Kim, Dongjun Chung

These results demonstrate that GPA-Tree can be a powerful tool that improves association mapping while facilitating understanding of the underlying genetic architecture of complex traits and potential mechanisms linking risk-associated SNPs with complex traits.

Network-based Topic Interaction Map for Big Data Mining of COVID-19 Biomedical Literature

1 code implementation7 Jun 2021 Yeseul Jeon, Dongjun Chung, Jina Park, Ick Hoon Jin

The application of this proposed framework to the PubMed literature demonstrates utility of our approach in understanding of the topic composition related to COVID-19 studies in the stage of its emergence.

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