Search Results for author: Eli Newby

Found 3 papers, 1 papers with code

Boolean Networks as Predictive Models of Emergent Biological Behaviors

no code implementations19 Oct 2023 Jordan C. Rozum, Colin Campbell, Eli Newby, Fatemeh Sadat Fatemi Nasrollahi, Reka Albert

Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory networks to species in ecological networks) and the often-incomplete state of system knowledge (e. g., the unknown values of kinetic parameters for biochemical reactions).

Structure-based approach can identify driver nodes in ensembles of biologically-inspired Boolean networks

no code implementations8 Mar 2023 Eli Newby, Jorge Gómez Tejeda Zañudo, Réka Albert

Driving a network's feedback vertex set (FVS) by node-state override into a state consistent with a target attractor is proven to force every system trajectory to the target attractor, but in biological networks, the FVS is typically larger than can be realistically manipulated.

Feedback Vertex Set (FVS)

Structure-based approach to identifying small sets of driver nodes in biological networks

1 code implementation22 Nov 2021 Eli Newby, Jorge Gómez Tejda Zañudo, Réka Albert

Thus, we developed an approach to rank subsets of the FVS on Boolean models of intracellular networks using topological, dynamics-independent measures.

Feedback Vertex Set (FVS)

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