Search Results for author: Federica Ferretti

Found 2 papers, 0 papers with code

Universal characterization of epitope immunodominance from a multi-scale model of clonal competition in germinal centers

no code implementations17 Oct 2023 Federica Ferretti, Mehran Kardar

We describe the evolution of the B cell population via a quasispecies dynamics, with species corresponding to unique B cell receptors (BCRs), where the desired multi-scale structure is reflected on the mutational connectivity of the accessible BCR space, and on the statistical properties of its fitness landscape.

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