Search Results for author: Jay D. Humphrey

Found 5 papers, 0 papers with code

G2Φnet: Relating Genotype and Biomechanical Phenotype of Tissues with Deep Learning

no code implementations21 Aug 2022 Enrui Zhang, Bart Spronck, Jay D. Humphrey, George Em Karniadakis

Many genetic mutations adversely affect the structure and function of load-bearing soft tissues, with clinical sequelae often responsible for disability or death.

Neural operator learning of heterogeneous mechanobiological insults contributing to aortic aneurysms

no code implementations8 May 2022 Somdatta Goswami, David S. Li, Bruno V. Rego, Marcos Latorre, Jay D. Humphrey, George Em Karniadakis

Thoracic aortic aneurysm (TAA) is a localized dilatation of the aorta resulting from compromised wall composition, structure, and function, which can lead to life-threatening dissection or rupture.

Operator learning

What do cells regulate in soft tissues on short time scales?

no code implementations9 Apr 2021 Jonas F. Eichinger, Daniel Paukner, Roland C. Aydin, Wolfgang A. Wall, Jay D. Humphrey, Christian J. Cyron

Cells within living soft biological tissues seem to promote the maintenance of a mechanical state within a defined range near a so-called set-point.

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