Molecular mechanism of anion permeation through aquaporin 6

no code implementations • 8 Nov 2023 • Eiji Yamamoto, Keehyoung Joo, Jooyoung Lee, Mark S. P. Sansom, Masato Yasui

Moreover, we demonstrate the pH-sensing mechanism in which the protonation of H184 and H189 under low pH conditions allosterically triggers the gating of the SF region.

The influence of geometry, surface character and flexibility on the permeation of ions and water through biological pores

1 code implementation • 25 Feb 2004 • Oliver Beckstein, Mark S. P. Sansom

By increasing the polarity of the pore wall (and thus reducing its hydrophobicity) the transition radius can be decreased until for hydrophilic pores liquid water is stable down to a radius comparable to a water molecule's radius.

Subcellular Processes Biological Physics