GORDA: Graph-based ORientation Distribution Analysis of SLI scatterometry Patterns of Nerve Fibres

no code implementations • 12 Apr 2022 • Esteban Vaca, Miriam Menzel, Katrin Amunts, Markus Axer, Timo Dickscheid

Scattered Light Imaging (SLI) is a novel approach for microscopically revealing the fibre architecture of unstained brain sections.

Scattered Light Imaging: Resolving the substructure of nerve fiber crossings in whole brain sections with micrometer resolution

1 code implementation • 3 Aug 2020 • Miriam Menzel, Jan André Reuter, David Gräßel, Mike Huwer, Philipp Schlömer, Katrin Amunts, Markus Axer

We demonstrate in different brain samples (human optic tracts, vervet monkey brain, rat brain) that the 2D fiber directions can be reliably reconstructed for up to three crossing nerve fiber bundles in each image pixel with an in-plane resolution of up to 6. 5 $\mu$m.

Medical Physics Biological Physics Optics