no code implementations • 23 May 2024 • Alex Morehead, Nabin Giri, Jian Liu, Jianlin Cheng
The effects of ligand binding on protein structures and their in vivo functions carry numerous implications for modern biomedical research and biotechnology development efforts such as drug discovery.
no code implementations • 16 Sep 2022 • Nabin Giri, Raj S. Roy, Jianlin Cheng
Cryo-Electron Microscopy (cryo-EM) has emerged as a key technology to determine the structure of proteins, particularly large protein complexes and assemblies in recent years.
1 code implementation • 26 May 2022 • Elham Soltanikazemi, Raj S. Roy, Farhan Quadir, Nabin Giri, Alex Morehead, Jianlin Cheng
Utilizing true contacts as input, DRLComplex achieved high average TM-scores of 0. 9895 and 0. 9881 and a low average interface RMSD (I_RMSD) of 0. 2197 and 0. 92 on the two datasets, respectively.