no code implementations • 4 Feb 2021 • Pierre Ronceray, Sheng Mao, Andrej Košmrlj, Mikko P. Haataja
Demixing of multicomponent biomolecular systems via liquid-liquid phase separation (LLPS) has emerged as a potentially unifying mechanism governing the formation of several membrane-less intracellular organelles ("condensates"), both in the cytoplasm (e. g., stress granules) and in the nucleoplasm (e. g., nucleoli).
Soft Condensed Matter Biological Physics
no code implementations • 4 Jan 2021 • Pierre Ronceray, Yaojun Zhang, Xichong Liu, Ned S. Wingreen
Multivalent associative proteins with strong complementary interactions play a crucial role in phase separation of intracellular liquid condensates.
Soft Condensed Matter Biological Physics
1 code implementation • 16 Feb 2020 • David B. Brückner, Pierre Ronceray, Chase P. Broedersz
Many complex systems, ranging from migrating cells to animal groups, exhibit stochastic dynamics described by the underdamped Langevin equation.
Biological Physics Soft Condensed Matter Statistical Mechanics Cell Behavior Quantitative Methods
1 code implementation • 27 Jan 2019 • Bin Xu, Guanhua He, Benjamin G. Weiner, Pierre Ronceray, Yigal Meir, Martin C. Jonikas, Ned S. Wingreen
One class of such condensates is composed of two polymer species, where each consists of repeated binding sites that interact in a one-to-one fashion with the binding sites of the other polymer.
Biological Physics Soft Condensed Matter Subcellular Processes
