Search Results for author: Rayanne A. Luke

Found 3 papers, 0 papers with code

Prevalence estimation methods for time-dependent antibody kinetics of infected and vaccinated individuals: a graph-theoretic approach

no code implementations13 Apr 2024 Prajakta Bedekar, Rayanne A. Luke, Anthony J. Kearsley

Immune events such as infection, vaccination, and a combination of the two result in distinct time-dependent antibody responses in affected individuals.

Optimal classification and generalized prevalence estimates for diagnostic settings with more than two classes

no code implementations5 Oct 2022 Rayanne A. Luke, Anthony J. Kearsley, Paul N. Patrone

The classification process is challenging when the relative fraction of the population in each class, or generalized prevalence, is unknown.

Classification

Modeling in higher dimensions to improve diagnostic testing accuracy: theory and examples for multiplex saliva-based SARS-CoV-2 antibody assays

no code implementations28 Jun 2022 Rayanne A. Luke, Anthony J. Kearsley, Nora Pisanic, Yukari C. Manabe, David L. Thomas, Christopher D. Heaney, Paul N. Patrone

We combine these models with optimal decision theory to yield a classification scheme that better separates positive and negative samples relative to traditional methods such as confidence intervals (CIs) and receiver operating characteristics.

Classification

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